Α-Methyltryptamine (also known as Indopan and usually as αMT or aMT Succinate) is an unpopular entactogen in the tryptamine class.
αMT was originally synthesized by Upjohn in the early 1960s. It was at times used in the Soviet Union as an antidepressant under the trade name Indopan. Indopan has been prescribed in dosages of 5-10 mg, which is significantly lower than the dosage used for recreational effects.
Erowid has received “a few unverifiable reports of hospitalization following high-dose aMT Succinate ingestion (over 60 mg orally)”. There are also 22 αMT-related deaths in England and Wales, where the drug gained popularity as a licensed drug in 2012 until it was banned in early 2015.
Very little data is available on the pharmacological properties, metabolism, and toxicity of aMT Succinate, and it has a limited history of non-medical human use. It is strongly recommended to use harm reduction practices while using this substance.
Chemistry of aMT Succinate
aMT drug or α-methyltryptamine is a synthetic indole alkaloid molecule of the tryptamine class. Tryptamines have a main structure consisting of a bicyclic indole heterocycle attached at R3 to an amino group via an ethyl side chain. aMT Succinate is substituted at the alpha Rα carbon of its tryptamine backbone by a methyl group.
aMT Succinate reddit is available as the free base as a racemate of its (R-) and (S-) enantiomers.
The psychedelic effects of aMT Succinate erowid are believed to stem from its efficacy on the 5-HT2A receptor as a partial agonist.
αMT also acts as a serotonin, norepinephrine and dopamine releasing agent. It also acts as a very weak and non-selective RIMA in vitro and in vivo., But this is unlikely to be very significant (if at all) with usual doses.
Disclaimer: The effects listed below relate to the Subjective Effects Index (SEI), a literature that draws on anecdotal reports gathered and the personal experiences of ChemicalsRetailer contributors. Therefore, they must be taken with great skepticism. It should be noted that these effects will not necessarily occur consistently or quite reliably, although larger doses (common +) are more likely to induce the full spectrum of reported effects. At the same time, side effects become much more noticeable with higher doses and can include critical injury or death.
5g, 10g, 15g, 25g, 50g